Advances in single-pixel imaging toward biological applications

2014 Summer.In this work, we discuss two new methods for single-pixel imaging. First, we leverage advances in laser metrology and frequency synthesis to measure small shifts in the center frequency of an optical pulse. Pulses acquire such shifts when probing a transient optical susceptibility, as in impulsive stimulated Raman scattering, which we use to demonstrate the technique. We analyze the limits of this technique with regard to fundamental noise, and predict detection sensitivity in these limiting cases. We then present work on imaging in two dimensions, both x-y and x-z, using single element detectors. We accomplish this by multiplexing spatial frequency projections in time, allowing rapid two dimensional imaging without an imaging detector. As we eliminate the imaging detector, the sensitivity to scattering is dramatically decreased, allowing the method to be used deep in scattering tissue. Results are shown for several geometries and experimental configurations, demonstrating imaging capabilities across a variety of sample types, including fluorescent and biological samples

The Solar Neighborhood. XXXIV. A Search for Planets Orbiting Nearby M Dwarfs using Astrometry

Astrometric measurements are presented for seven nearby stars with previously detected planets: six M dwarfs (GJ 317, GJ 667C, GJ 581, GJ 849, GJ 876, and GJ 1214) and one K dwarf (BD $-$10 3166). Measurements are also presented for six additional nearby M dwarfs without known planets, but which are more favorable to astrometric detections of low mass companions, as well as three binary systems for which we provide astrometric orbit solutions. Observations have baselines of three to thirteen years, and were made as part of the RECONS long-term astrometry and photometry program at the CTIO/SMARTS 0.9m telescope. We provide trigonometric parallaxes and proper motions for all 16 systems, and perform an extensive analysis of the astrometric residuals to determine the minimum detectable companion mass for the 12 M dwarfs not having close stellar secondaries. For the six M dwarfs with known planets, we are not sensitive to planets, but can rule out the presence of all but the least massive brown dwarfs at periods of 2 - 12 years. For the six more astrometrically favorable M dwarfs, we conclude that none have brown dwarf companions, and are sensitive to companions with masses as low as 1 $M_{Jup}$ for periods longer than two years. In particular, we conclude that Proxima Centauri has no Jovian companions at orbital periods of 2 - 12 years. These results complement previously published M dwarf planet occurrence rates by providing astrometrically determined upper mass limits on potential super-Jupiter companions at orbits of two years and longer. As part of a continuing survey, these results are consistent with the paucity of super-Jupiter and brown dwarf companions we find among the over 250 red dwarfs within 25 pc observed longer than five years in our astrometric program.Comment: 18 pages, 5 figures, 4 tables, accepted for publication in A

Active Stars in the Spectroscopic Survey of Mid-to-Late M Dwarfs Within 15pc

We present results from the volume-complete spectroscopic survey of 0.1-0.3M$_\odot$ M dwarfs within 15pc. This work discusses the active sample without close binary companions, providing a comprehensive picture of these 123 stars with H${\alpha}$ emission stronger than -1\unicode{xC5}. Our analysis includes rotation periods (including 31 new measurements), H${\alpha}$ equivalent widths, rotational broadening, inclinations, and radial velocities, determined using high-resolution, multi-epoch spectroscopic data from the TRES and CHIRON spectrographs supplemented by photometry from TESS and MEarth. Using this volume-complete sample, we establish that the majority of active, low-mass M dwarfs are very rapid rotators: specifically, 74$\pm$4% have rotation periods shorter than 2 days, while 19$\pm$4% have intermediate rotation periods of 2-20 days, and the remaining 8$\pm$3% have periods longer than 20 days. Among the latter group, we identify a population of stars with very high H${\alpha}$ emission, which we suggest is indicative of dramatic spindown as these stars transition from the rapidly to slowly rotating modes. We are unable to determine rotation periods for six stars and suggest that some of the stars without measured rotation periods may be viewed pole-on, as such stars are absent from the distribution of inclinations we measure; this lack notwithstanding, we recover the expected isotropic distribution of spin axes. Our spectroscopic and photometric data sets also allow us to investigate activity-induced radial-velocity variability, which we show can be estimated as the product of rotational broadening and the photometric amplitude of spot modulation.Comment: Accepted for publication in AJ; 18 pages, 12 figures, 3 table

Observations of Binary Stars with the Differential Speckle Survey Instrument. V. Toward an Empirical Metal-Poor Mass-Luminosity Relation

In an effort to better understand the details of the stellar structure and evolution of metal poor stars, the Gemini North telescope was used on two occasions to take speckle imaging data of a sample of known spectroscopic binary stars and other nearby stars in order to search for and resolve close companions. The observations were obtained using the Differential Speckle Survey Instrument, which takes data in two filters simultaneously. The results presented here are of 90 observations of 23 systems in which one or more companions was detected, and 6 stars where no companion was detected to the limit of the camera capabilities at Gemini. In the case of the binary and multiple stars, these results are then further analyzed to make first orbit determinations in five cases, and orbit refinements in four other cases. Mass information is derived, and since the systems span a range in metallicity, a study is presented that compares our results with the expected trend in total mass as derived from the most recent Yale isochrones as a function of metal abundance. These data suggest that metal-poor main-sequence stars are less massive at a given color than their solar-metallicity analogues in a manner consistent with that predicted from the theory

Impacts of Bicycle Infrastructure in Mid-Sized Cities (IBIMS): protocol for a natural experiment study in three Canadian cities

Introduction: Bicycling is promoted as a transportation and population health strategy globally. Yet bicycling has low uptake in North America (1%–2% of trips) compared with European bicycling cities (15%–40% of trips) and shows marked sex and age trends. Safety concerns due to collisions with motor vehicles are primary barriers.  To attract the broader population to bicycling, many cities are making investments in bicycle infrastructure. These interventions hold promise for improving population health given the potential for increased physical activity and improved safety, but such outcomes have been largely unstudied. In 2016, the City of Victoria, Canada, committed to build a connected network of infrastructure that separates bicycles from motor vehicles, designed to attract people of ‘all ages and abilities’ to bicycling.  This natural experiment study examines the impacts of the City of Victoria’s investment in a bicycle network on active travel and safety outcomes. The specific objectives are to (1) estimate changes in active travel, perceived safety and bicycle safety incidents; (2) analyse spatial inequities in access to bicycle infrastructure and safety incidents; and (3) assess health-related economic benefits.  Methods and analysis: The study is in three Canadian cities (intervention: Victoria; comparison: Kelowna, Halifax). We will administer population-based surveys in 2016, 2018 and 2021 (1000 people/city). The primary outcome is the proportion of people reporting bicycling. Secondary outcomes are perceived safety and bicycle safety incidents. Spatial analyses will compare the distribution of bicycle infrastructure and bicycle safety incidents across neighbourhoods and across time. We will also calculate the economic benefits of bicycling using WHO’s Health Economic Assessment Tool.  Ethics and dissemination: This study received approval from the Simon Fraser University Office of Research Ethics (study no. 2016s0401). Findings will be disseminated via a website, presentations to stakeholders, at academic conferences and through peer-reviewed journal article